![]() We used our cheesy garlic vegan alfredo sauce as major inspiration for this.Īdd the cooked macaroni to your big pot of sauce and toss it all together and then transfer into a 9×13 baking dish, top with breadcrumbs and bake for 20 minutes until beautifully golden brown on top. ![]() The spices in this sauce really make it, you won’t have any doubt that this is a cheese sauce. I created a bechamel sauce with some vegan butter, all purpose flour, coconut milk and vegetable stock and once that was thick and creamy like a white sauce should be, I added some cheesy flavorings in the form of dijon mustard, nutritional yeast, onion powder, garlic powder, smoked paprika, salt and pepper. I did try a version with some vegan cheese added to the sauce, and quite honestly I just didn’t think it worked as well as the version without, so this is it. So if you’re living somewhere where it’s hard to find vegan cheese in the supermarket, no worries, this recipe is for you. This vegan mac and cheese is ultra cheesy yet we did not use one shred of actual vegan cheese in it. We made a vegan bechamel sauce and added all sorts of cheesy flavorings to it in lieu of actual cheese so that even non-vegans will find this cheesy as all heck, and then we topped it with delicious breadcrumbs and baked it. This is really a ‘classic’ vegan mac and cheese recipe in the sense that a classic mac and cheese usually involves a bechamel sauce with heaps of cheese added to it, and then it’s placed into a dish and topped with breadcrumbs and baked.Īnd that’s really very close to what we did here. It’s creamy, saucy, ultra cheesy and topped with a delicious crispy breadcrumb topping and baked to perfection. This classic baked vegan mac and cheese is everything you want a mac and cheese to be. Topped with breadcrumbs and baked until golden brown and crispy. This classic vegan mac and cheese is ultra cheesy, saucy and creamy.
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It heralds the arrival of a director to watch out for and promises bigger roles for its two main leads. Presently, its narrative weight unbalances the overall emotional arc of the film.īut the deliberate nature of the narrative, barring these missteps, largely serves to elevate Calibre’s impact. The film could have gained by offering a few more clues about the emotional finale that awaited us. So when the ending arrives, while never entirely unpredictable, it seeks to shatter the sense of warmth we’d grown accustomed to. The switching emotional gears and the occasional overturning of genre expectations never threatens to derail the patina of warmth it continues to offer us. Throughout its runtime, Calibre appears to assure us about its purpose. The bromance goes horribly wrong and the final image of Vaughn, his face lashed by terror and guilt, goes deeper into the conscience than any gory sequence ever can. Vaughn suffers under the yoke of the past and the future and when they become too much for him, events take an even more tragic turn. Do they know? What if they don’t? Should we confess? Should we not? Oh and then there’s the baby. ![]() ![]() The uncertainty of the implications of their actions threatens to upend their chances of making it out safely from Dodge. The locals’ confusion in particular drives Vaughn into fear and despair. He leaves it hanging like a little, red thread over the picture, preferring to focus on his characters’ moral ambivalence following the tragedy. ![]() Palmer never dwells on this theme for too long. Coupled with Marcus’ arrogance, it serves to heighten the confusion they face while hosting the duo. The locals are aware of the possibilities and implications of his presence. Marcus comes with the promise of bringing business into the small town. Palmer also lodges economic and moral conflicts into the narrative with great ease. Calibre’s great achievement thus becomes its honest denouement, perfectly justified, however brutal it may appear at first sight.įrom real-life connection to reel-life equation: Vijay Varma & Tamannaah are all set to steal the show in Lust Stories 2 Harry and Meghan developing a ‘Great Expectations’ prequel for Netflix after parting ways with Spotify But Palmer’s unwavering attention to the dynamics between his two characters and their cat and mouse with the locals creates an atmosphere that sucks you in for good. It will be a stretch to claim that the seasoned film watcher won’t be able to see the ending coming in advance. Slowly and steadily, with the patience of a sculptor, Palmer works away at their personalities till their true selves are revealed to the audience. Jack Lowden and Martin McCann’s portrayal of Vaughn and Marcus, characters whose need to balance the audience’s empathy and disgust is no easy task, elevates Calibre. Hereon, Palmer veers away from genre expectations, switching emotional gears expertly and plunging the protagonists and his audience down a rabbit hole of guilt, misery and utter fear. It is cut short by a tragedy that triggers the film into a new, harrowing direction. Predictably, the deer hunt doesn’t go according to plan. A drunken night of revelry ends in a romp with a couple of local girls, which only serves to upset the townsfolk further. Image via soon as Marcus and Vaughn drive into their inn at Dodge, a sleepy little town nestled in the highlands, it becomes clear that they aren’t quite welcome there. I also use the Calibre program, as installed on my Windows notebook, to download works from a variety of fanfiction websites (including AO3) and convert those to PDF file format.A still from Calibre. If you are curious you can use Calibre to make your own and make them all pretty. ![]()
Previous studies have found that nonmydriatic digital retinal imaging alone exhibits performance comparable with dilated fundus examination and with dilated fundus photography for the detection of diabetic retinopathy. Retinal imaging (fundus photography) has been used extensively in photodocumentation for clinical purposes, as well as in research, telemedicine, and patient education during routine eye care. 1 – 4 The use of nonmydriatic digital retinal imaging in the assessment and management of ocular disease is becoming increasingly widespread. Timely detection and treatment of ocular disease can lower the risk of vision loss and reduce health care costs, particularly for those with diabetes and those at risk for age-related macular degeneration and glaucoma. When the methods disagreed, the results indicated a statistically significant advantage for the image-assisted examination in detecting suspicious cupping ( P = 0.04), drusen in the posterior pole/macula and mid-to-peripheral retina ( P = 0.004, P < 0.001), retinal pigment epithelial changes in the posterior pole/macula ( P = 0.04), nevi in the posterior pole/macula and mid-to-peripheral retina ( P = 0.01, P = 0.007), peripheral retinal degeneration ( P < 0.001), hemorrhage in the mid-to-peripheral retina ( P = 0.01), and vitreous lesions ( P < 0.001). Agreement was poor for hemorrhage in the mid-to-peripheral retina (kappa 0.33), and nevi in the mid-to-peripheral retina (0.34). Agreement between image-assisted and traditional fundus examination varied by lesion type and was excellent for staphyloma (kappa 0.76), fair for suspicious cupping (kappa 0.66), drusen in the posterior pole/macula and mid-to-peripheral retina (0.45, 0.41), retinal pigment epithelial changes in the posterior pole/macula (0.54), peripheral retinal degeneration (0.50), cobblestone (0.69), vitreoretinal interface abnormalities (0.40), and vitreous lesions (0.53). This is a 2021 ARVO Annual Meeting abstract.In total, 170 subjects (339 eyes) were recruited. Analysis of the retinal images will determine their correlations with other medical tests, including cognitive testing, nutrition, and biologic biomarkers. Future work will assess the influences of socioeconomic status and race on eye disease. Moderate visual impairment was seen in 51 (11.9%) participants who had VA between 20/50 and 20/200 in the better seeing eye.įundus photography in this cohort identified potential ocular pathology with recommendation for follow-up with an ophthalmologist in about half of participants. Of the 427 participants with VA data, the majority (375 87.8%) had VA ≥20/40 in at least one eye. ![]() ![]() Cup-to-disc ratios of the optic nerves were graded as ≥0.5 in 434/1761 eyes (24.6%). Roughly half of eyes (1018) were found to have abnormal findings, most commonly glaucoma/glaucoma suspect (295 eyes ), hypertensive retinopathy (156 eyes ), macular degeneration (100 eyes ), and retinal hemorrhage (39 eyes, ). The image quality was gradable in 1646/1930 (85.3%) of photos. The participants were 60.8% women (587) and 63.4% African American (612). Data were analyzed using R statistical software.Ī total of 965 participants (mean age: 59.3☘.8 years) underwent fundus photography. Presenting visual acuities (VA) were collected beginning in 2019. The images were graded by ophthalmologists who were masked to the other clinical data. Participants in wave 5 also underwent color fundus photography (TopCon TRC-NW400 non-mydriatic camera) at their study visit. Detailed testing is performed to assess nutrition, cognition, and biologic biomarkers. ![]() In the HANDLS study, mobile research vehicles are used to evaluate all participants every 4 years. An ophthalmic component was added in 2017 to evaluate the prevalence and characteristics of eye disease in this population. ![]() Participants are urban African American and white adults recruited from 13 neighborhoods in Baltimore City. The Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study is an ongoing prospective cohort study initiated in 2004 to evaluate the influences of socioeconomic status and race on the incidence of age-related diseases in the United States. |
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